Risk factors for non-vancomycin-resistant enterococcus faecium infection

Results We studied 841 patients, 21 of them (2.5 %) with an E. Faecium infection. No E. faecium vancomycin resistance was found. Patients with E. Faecium isolation were older (69.5 vs 64), infections had been acquired in the hospital, were surgical patients in higher proportion and had longer ICU stay (81 vs 44.3 % p 0.001 and 57.1 vs 27.5 % p 0.003 and 6 (3-11) vs 13 (6-25) p 0.001 respectively), had received parenteral nutrition (43 v 13 % p 0.001) and were malnourished in higher rate (25 v 4.2 % p 0.001) Prior use of piperacilina-tazobactam, carbapenem or linezolid were found more frequently in E. Faecium-infected patients (52.4 vs 24.1 % p 0.003 and 66.7 vs 20.6 % p 0.001) ESBL isolation coexisted more frequently in patients with E. Faecium infection. Mortality rate was higher in patients with E. faecium infection (57 vs 25.6 % p 0.001). Logistic regression analysis showed nosocomial admission, prior use of piperaciline-tazobactam or carbapenem and ESBL isolation as independent risk factors for E. faecium infection. E. faecium infection was not independently associated with mortality.